Dr. Gul-e-Saba Chaudhry

Dr. Gul-e-Saba Chaudhry is a highly accomplished professional, specializing in the domains of biochemistry, molecular biology, drug discovery, and drug delivery. Holding a prestigious postdoctoral fellowship from the Institute of Marine Biotechnology (IMB) at the University of Management and Technology (UMT) in Malaysia, Dr. Chaudhry has dedicated Dr research efforts to the synthesis of anticancer drug nanoparticles and their profound implications on programmed cell death within cancer cells.

With a robust academic foundation, Dr. Chaudhry obtained Ph.D. in Chemical Engineering from Universiti Teknologi PETRONAS and earned a master’s degree in molecular Genetics/Biochemistry from Quaid-e-Azam University in Pakistan. Dr expertise extends across various advanced methodologies, including high-content screening assays, in vitro cytotoxicity experiments, and the nuanced optimization of experimental protocols.

Dr. Chaudhry has garnered recognition for scholarly contributions, reflected in a multitude of publications in reputable journals. These publications span critical topics such as cancer, apoptosis, and drug delivery systems, showcasing Dr dedication to advancing scientific knowledge.

Active participation in conferences, both as a distinguished participant and presenter, underscores Dr. Chaudhry's commitment to disseminating knowledge and fostering dialogues within Dr field. The professional trajectory encompasses roles as a postdoctoral fellow, assistant professor, and visiting faculty at esteemed institutions in Malaysia and Pakistan. In acknowledgment of Dr academic prowess, Dr. Chaudhry has received scholarships and awards, further solidifying standing in the academic community.

Beyond Dr individual achievements, Dr. Chaudhry has also assumed a mentoring role, guiding Ph.D. students under supervision. A testament to commitment to excellence, Dr has secured a grant for a multi-targeted mechanistic study focusing on cancer cells, showcasing enduring impact on the forefront of biochemistry and cancer therapeutics research.

LIST OF PUBLICATIONS
  1. 1. Gul-e-Saba Chaudhry*, Yeong Yik Sung, and Muhammad TST. Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics Front Pharmacol. 2022; 13: 842376.
  2. 2. Gul-e-Saba Chaudhry, Yeong Yik Sung, and Muhammad TST. Carbon Stock Estimation of Selected Subtropical Broad-Leaved Evergreen Scrub Forest. Sustainability 2022, 14(18), 11219
  3. 3. Gul-e-Saba Chaudhry, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad, Cancer and Apoptosis, Methods in Molecular Biology book series (MIMB,volume 2543) Humana, New York, NY
  4. 4. Rabia Mehmood Rabia Mehmood Gul-e-Saba Chaudhry*, Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies. ACS Omega. 2022.
  5. 5. Gul-e-Saba Chaudhry,* Abdah Akim, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad. Polymeric Nanoparticles methods of Preparation and Drug Release Models: Effectiveness towards Drug Delivery Systems. Research Journal of Pharmacy and Technology. 2022 Accepted, In press
  6. 6. Gul-e-Saba Chaudhry*; Thirukanthan CS; Nor Atikah Mohamed Zin; Effendy AWM, Research Journal of Pharmacy and Technology. Antibacterial activity of Chito oligosaccharides Derived from Fish Scales Research Journal of Pharmacy and Technology. 2022
  7. 7. Gul-e-Saba Chaudhry*; Thirukanthan CS; Nor Atikah Mohamed Zin; Yeong Yik Sung1; Tengku Sifzizul Tengku Muhammad; Effendy AWM. Antibacterial activity of Tilapia Fish Scales derived Chitosan; Future towards Biomedicines. Research Journal of Pharmacy and Technology. Research Journal of Pharmacy and Technology. 2022
  8. 8. Gul-e-Saba Chaudhry*; Chito-oligosaccharides derived from Tilapia fish scales; Powerful Antioxidant. Thirukanthan CS; Nor Atikah Mohamed Zin; Yeong YikSung1; Tengku Sifzizul Tengku Muhammad; Effendy AWM. Research Journal of Pharmacy and Technology. 2022
  9. 9. Gul-e-Saba Chaudhry*, Yeong Yik Sung, and Muhammad TST. Understanding Nanotechnology and Apoptosis in Cancer Therapeutics. BUKU IMB, UMT
  10. 10. Chaudhry GE*, Thirukanthan C.S., Murni NurIslamiah K1., Effendy A.W.M., Yeong Yik Sung, and Muhammad TST. Characterization and Cytotoxicity of Low Molecular Weight Chitosan and Chito-oligosaccharides derived from Tilapia fish scales. 2021 Journal of Advanced Pharmaceutical Technology & Research.
  11. 11. Gul-e-Saba Chaudhry, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad, Pd(II) complexes with chelating N-(1-alkylpyridin-4(1H)-ylidene)amide (PYA) ligands: Synthesis, characterization and evaluation of anticancer activity, Journal of Inorganic Biochemistry, 224, 2021, 111590
  12. 12. Chaudhry GE. Development of biodegradable thin films for efficient, specific andcontrolled delivery of capecitabine. Biomed Mater. 2021 Aug 31;16(5).
  13. 13. Chaudhry, GeS. et al. Radical Scavenging Capability Influences the Multifarious Therapeutic Tendencies of Phyto-Engineered CuO Nanostructures. J Inorg Organomet Polym (2021).
  14. 14. Gul-e-Saba Chaudhry*, Murni Islamiah, Muhammad Naveed Zafar, Habsah Mohamad, Noraznawati Ismail, Yeong Yik Sung and Tengku Sifzizul Tengku Muhammad. Induction of apoptosis by Acanthaster planci sp., and Diadema setosum sp., fractions in human cervical cancer cell line, HeLa In press Asian Pac J Cancer Prev 2021.
  15. 15. Gul-e-Saba Chaudhry*, Nur Khairina Ahmed Sohimi, Habsah Mohamad, Muhammad Naveed Zafar, Aziz Ahmed, Yeong Yik Sung, Tengku Sifzizul Tengku
  16. 16. Muhammad Xylocarpus moluccensis induces cytotoxicity in human hepatocellular carcinoma HepG2 cell line via activation of the extrinsic pathway Asian Pac J Cancer Prev. 2021 Feb 1;22(S1):17-24.
  17. 17. Kazmi, Z., Safdar, N., Chaudhry, GeS. et al. Radical Scavenging Capability Influences the Multifarious Therapeutic Tendencies of Phyto-Engineered CuO Nanostructures. J Inorg Organomet Polym (2021).
  18. 18. Gul-e-Saba Chaudhry*, Abdah Akim, Naveed zafar, Yeong Yik Sung, Muhammad TST. Understanding HA-CD44 interaction, HA-CD44 activated potential targets in cancer progression and future therapeutics. Adv Pharm Bull 2021.
  19. 19. Gul-e-Saba Chaudhry*, Yeong Yik Sung, Muhammad TST, Yeong Yik Sung. Breast cancer: Plant derived anti-cancer agents as breast-cancer therapeutics, Adv Pharm Bull 2021.
  20. 20. M. Imran, Z.U. Rehman, G. Hogarth, D.A. Tocher, G.S. Chaudhry, I.S. Butler, F.B. Gariepy, T. Kondratyuk Two new monofunctional platinum(II) dithiocarbamate complexes: phenanthriplatin-type axial protection, equatorial-axial conformational isomerism, anticancer and DNA binding studies Dalton Transacrions, 49 (2020), pp. 15385-15396
  21. 21. Gul-e-Saba Chaudhry*, Nurul Huda Rahman, S Vigneswari, Ahmad Aziz, M Habsah, Yeong Yik Sung. TMT Sifzizul Cytotoxicity Effect and Cell Death Mechanism of Bruguiera gymnorrhiza Extracts on Human Breast Cancer Cell Line (MCF-7) J Adv Pharm Technol Res. 2020 Oct-Dec;11(4):233-237.
  22. 22. Gul-e-Saba Chaudhry*, Murni Islamiah, Muhammad Naveed Zafar, Habsah Mohamad, Noraznawati Ismail, Yeong Yik Sung and Tengku Sifzizul Tengku Muhammad. Induction of apoptosis by Acanthaster planci sp., and Diadema setosum sp., fractions in human cervical cancer cell line, HeLa In press Asian Pac J Cancer Prev 2021
  23. 23. Gul-e-Saba Chaudhry*, Abdah Akim, Navved zafar, Yeong Yik Sung, Muhammad TST. Understanding HA-CD44 interaction, HA-CD44 activated potential targets in cancer progression and future therapeutics. In press Adv Pharm Bull 2021.
  24. 24. Gul-e-Saba Chaudhry*, Abdah Md Akim, Muhammad Naveed Zafar, MA Abdullah, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad, (2020) Induction of Apoptosis and role of PTX loaded HA-crosslinked nanoparticle in the regulation of AKT and RhoA. J Adv Pharm Technol Res. 2020 Jul-Sep;11(3):101-106.
  25. 25. Gul-e-Saba Chaudhry*, Nur Khairina Ahmed Sohimi, Habsah Mohamad, Muhammad Naveed Zafar, Aziz Ahmed, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad Xylocarpus moluccensis induces cytotoxicity in human hepatocellular carcinoma HepG2 cell line via activation of the extrinsic pathway Asian Pac J Cancer Prev. 2021 Feb 1;22(S1):17-24.
  26. 26. Gul-e-Saba Chaudhry*, Zafar MN, Yeong Yik Sung, Muhammad TST Phytochemistry and Biological activity of Vitex rotundifolia L., Research J. Pharm. and Tech. 2020; 13(11):5534-5538.
  27. 27. Yunus, Uzma; Chaudhry, Gul-e-Saba Chaudhry*; Yeong Yik Sung, Muhammad TST. Targeted Drug Delivery Systems: Synthesis and In-Vitro Bioactivity and Apoptosis Studies of Gemcitabine-Carbon Dots Conjugates Biomed. Mater. 2020 Sep 7 26;15(6):065004.
  28. 28. Gul-e-Saba Chaudhry*, Nur Khairina Ahmed Sohimi, Zafar MN, Habsah M, Yeong Yik Sung, Muhammad TST. Induction of apoptosis by selected Xylocarpus sp., fractions in the human cervical cancer cell line, HeLa. Int J Res Pharm Sci, 2020 11(2): 2332-2339.
  29. 29. Gul-e-Saba Chaudhry*, Murni NIK, Zafar MN, Habsah M, Yosie A, Noraznawati I, Yeong Yik Sung, TST Muhammad, (2020). Induction of apoptosis by Stichopus chloronotus and Holothuria nobilis fractions in human cervical cancer cell line, HeLa. Int J Res Pharm Sci, 2020, 11(1), 1238-1247.
  30. 30. Andriani Yosie, Gul-e-Saba Chaudhry*, Oksal Efriyana, Pangestika Inten, Ramli Nadia Madiha, Mohamad Habsah, Elvia Rina, Amir Hermansyah, AWM Effendy, Sung Yeong Yik, Muhammad Tengku Sifzizul Tengku Antihypercholesterolemic and antiatherosclerotic potencies of Pandanus tectorius fruits via increasing scavenger receptor-B1 genes expression and inhibition of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity. J Adv Pharm Tecnol Res. 2020 (11); 30-35
  31. 31. Mahar J, Saeed A, Gul-e-Saba Chaudhry* et al. (2020) Synthesis, characterization and cytotoxic studies of novel 1,2,4-triazole-azomethine conjugates. J Iran Chem Soc
  32. 32. Zafar MN, Masood S, Gul-e-Saba Chaudhry*, Muhammad TST, Dalebrook AF, Nazar MF, Malik FP, Mughal EU, Wright LJ (2019) Synthesis, characterization and anti-cancer properties of water-soluble bis(PYE) pro-ligands and derived palladium(ii) complexes. Dalton Trans, 48, 15408-15418.
  33. 33. Gul-e-Saba Chaudhry*, Jan R, Habsah M, Mohammad T.S.T (2019a). Vitex rotundifolia fractions induce apoptosis in the human breast cancer cell line, MCF-7, via extrinsic and intrinsic pathways. Res Pharma Sci, 14(3), 273-285.
  34. 34. Gul-e-Saba Chaudhry*, Jan R, Zafar MN, Habsah M, Muhammad TST, (2019b). Vitex rotundifolia fractions induced apoptosis in human breast cancer T-47D cell line via activation of extrinsic and intrinsic pathway. Asian Pac J Cancer Prev, 3555-3562.
  35. 35. Gul-e-Saba Chaudhry* Jan R, and (2019). Understanding apoptosis and apoptotic pathways targeted cancer therapeutics. Adv Pharm Bull, 9(2), 205-218.
  36. 36. Zafar MN, Nazar MF, Mughal EU, Gul-e-Saba Chaudhry, Hina, K Synthesis, Characterization and catalytic activity of heteroleptic rhodium complex for C-N couplings. Accepted in Russian journal of coordination chemistry. 45, pages62–73(2019).
  37. 37. Gul-e-Saba*, Murni Ismail, Noraznawati Ismail, Habsah, Tengku Sifzizul Tengku Muhammad Induction of Apoptosis by Aaptos sp., fractions in human breast cancer. 2018. Int. J. Res. Pharm. Sci. 9(2), 328-237.
  38. 38. Perveen, safdar, Gul-e-Saba Chaudhry, yasmin. A. Antibacterial evaluation of silver nanoparticles synthesized from lychee peel: individual versus antibiotic conjugated effects. World Journal of Microbiology & Biotechnology 2018, 34(8): 118
  39. 39. Rehmat, Gul-e-Saba*, Safdar. Antitumor activity of aspartame in diet coke using potato disc tumor assay. J. Pharm. Sci. & Res. Vol. 10(8), 2018, 2119-2121.
  40. 40. Hudaya, T, Gul-e-Saba, Taib, M, Ismail, N, Mohammad, TST, 2017, Methanol extract of four selected marine sponges induces apoptosis in human breast cancer cell line, MCF-7. Int J Res Pharm Sci, 8(3), 667-675.
  41. 41. Zafar, M. N., Masood, S., Gul-e-Saba (2017), Solvent-free Synthesis of Water-Soluble New Pyridinium Amines: Spectroscopic Characterization, Biological Screening, and Interaction Study with DNA. Journal of the Chinese Chemical Society, 64: 822–832.
  42. 42. M. Naveed Zafar, Aftab Hussain Atif, M. Gul-e-Saba, Rizwan Paracha (2016). Pyridine and Related Ligands in Transition Metal Homogeneous Catalysis. Russian. Journal of Coordination Chemistry Volume 42, Issue 1, pp1-18.
  43. 43. M. Naveed Zafar, Aftab Hussain Atif, Gul-e-Saba, Sajjad Hussain Sumrra, M. Faizan Nazar (2016). Development of Some Important Nitrogen Donor Ligands for Transition Metal Homogeneous Catalysis. Russian Journal of Coordination Chemistry. 42, Issue 4, pp 225-251
  44. 44. Gul-e-Saba, A. Abdah, M.A. Abdullah. (2014). Synthesis, Characterization and Cytotoxicity of HA-PTX NPs on Cancer cell lines. Journal of Advance Chemical Engineering 4(1): 104.
  45. 45. Gul-e-Saba, A. Abdah, M.A. Abdullah (2010) Hyaluronan-mediated CD44 Receptor Cancer Cells Progression and the Application of Controlled Drug-delivery System, International Journal of Current Chemistry 1(4): 245-265.
Book Chapters

46. Gul-e-Saba Chaudhry, Anis Razak, Yeong Yik Sung, TST Muhammad. Nanotechnology and apoptosis in cancer therapeutics, Research trends in biotechnology and bioresources technology. 2022 in press

47. Gul-e-Saba Chaudhry, Abdah Akim, Yeong Yik Sung, TST Muhammad. Cancer and Apoptosis. Method in molecular biology. submitted

48. Gul-e-Saba, M.A. Abdullah, Polymeric Nanoparticle mediated Targeted Drug Delivery to cancer cells. Biotechnology and Bioinformatics Advances and Applications for energy, Bioremediation and Biopharmaceutical Research Hard ISBN: 9781771880015. (2014) Apple Academic Press, New Jersey, USA.